Chymotrypsin Inhibitor



Chymotrypsin Inhibitors (CI) are serine proteinase inhibitors of chymotrypsin. They are classified by numbers: CI-1, CI-2, CI-3. The images at the left and at the right correspond to one representative Chymotrypsin Inhibitor, i.e. the crystal structure of Chymotrypsin Inhibitor from Phosphocarpus tetragonolobus (4wbc).

3D Structures of Chymotrypsin Inhibitor
Update June 2011

CI-1
2jzm – CI-1 fragment – Nicotiana alata – NMR

1eai – CI-1+elastase - pig

1kgm –lCI-1 – locust

1kio – lCI-1 (mutant)

CI-2
1y1k, 1y33, 1y34, 1y3b, 1y3c, 1y3d, 1y3f, 1y48, 1y4a, 1y4d, 1tm1, 1tm3, 1tm4, 1tm5, 1tm7, 1tmg, 1to1, 1to2, 1lw6 – BaCI-2 (mutant)+subtilisin – Bacillus amyloliquefaciens

2sni - BaCI-2+subtilisin

1ciq, 1cir – HvCI-2 fragments – Hordeum vulgare

1coa, 1ypa, 1ypb, 1ypc – HvCI-2 (mutant)

1cis - HvCI-2+subtilisin helix – NMR

3ci2 - HvCI-2 – NMR

2ci2 - HvCI-2

1cq4 - HvCI-2 domain swap

CI-3
3i2a, 3i2x, 2bea, 2beb, 2esu, 2et2, 1xg6, 1fmz, 1fn0, 1eyl, 3qyd – PtCI-3 (mutant) – Phosphocarpus tetragonolobus

4wbc, 2wbc, 1wbc - PtCI-3

3i29 - PtCI-3 (mutant)+trypsin

2qyi – CI-3 (mutant)+cationic trypsin – cow

1ccv – CI –Apis mellifera - NMR